Actinomycetes in Biotechnology


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Actinomycetes: Role in Biotechnology and Medicine

So, our lasting struggle against infectious bacteria will still continue in future. We have been studying on Streptomyces by using various methods of biochemistry, molecular biology, and organic chemistry. The present main projects in our laboratory are as follows. We believe that these studies will contribute to produce new hybrid antibiotics with biological activity that are useful for human life.

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Arakawa received the 15th Hiroshima University President Award. Arakawa received the Nagase Award. Its life cycle includes the following stages:.


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Free spore remains dormant until the stage of germination. Vegetative Growth : The germ tube promotes a vegetative growth, which gives rise to the substrate and aerial hyphae.

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First, a germ tube will produce a primary mycelium i. Substrate hyphae , which grow within the media. After the growth of primary mycelium, it forms secondary mycelium i. Coiling : During unfavourable conditions, the aerial hyphae become spirally coiled. Septation : At this stage, septa forms between the vegetative hyphae.

Spore maturation : The septa forms within the vegetative hyphae maturates and forms a chain of spores. The spore thus forms by fragmentation or swelling of the hyphae. Release of spore : During the unfavourable condition, the spores get separated from the vegetative hyphae and are free in the environment.

Streptomycetaceae : Members of this family consist of non-segmented hyphae and consists of conidial spores per chain of aerial hyphae.

Streptomyces Molecular Biology and Biotechnology

Examples: Streptomyces , Microdlobaspone and Sporoctilhya. Nocardiaceae : Members of this family consist of typical non-segmented hyphae.

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Examples: Nocardia , Pseudonocardia. Micromonosporaceae : Members of this family consist of typical non-segmented conidia which occur singly, pairs or in chains. Examples: Micromonospora , Thermonospora , Thermoactinomycetes , Actinobifida. Actinoplanaceae : Members of this family consist sporangiospores and the diameter of hyphae ranges from 0. Examples: Streptosporangium , Actinoplanes , Plasmobispora and Dactylosporangium. Dermatophilaceae : Members of this family consist of hyphae which undergo fragmentation to produce a large number of motile structures.

Novel Bioactive Molecules from Marine Actinomycetes | Biosciences Biotechnology Research Asia

Examples: Geodermatophilus. Frankiaceae : Members of this family are strictly associated with the roots of a non-leguminous plant and helps in nitrogen fixation by forming root nodules. Example: Frankia. Actinomycetaceae : The members of this family do not contain true mycelium and are facultative anaerobes. Examples: Actinomyces. Actinomycetes is an economically important organism which plays a fundamental role in many areas like:.

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